Istradefylline 40 mg/day greater peak levels and AUC of CYP3A4 substrates in clinical trials. This outcome was not noticed with istradefylline 20 mg/day. Contemplate dose reduction of delicate CYP3A4 substrates.You should not use this medication In case you are allergic to doxepin, amoxapine, or loxapine, or When you've got:As a result, based on th